Combining a CAR and a chimeric costimulatory receptor enhances T cell sensitivity to low antigen density and promotes persistence.
Afroditi KatsarouMaria SjöstrandJyoti NaikJorge Mansilla-SotoDionysia KefalaGeorgios KladisAlexandros NianiasRuud RuiterRenée PoelsIrene SarkarYash R PatankarElena MerinoRogier M ReijmersKristine A FrerichsHuipin YuanJoost D de BruijnDina StroopinskyDavid AviganNiels W C J van de DonkSonja ZweegmanTuna MutisMichel SadelainRichard W J GroenMaria ThemeliPublished in: Science translational medicine (2021)
[Figure: see text].
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