Michel Sadelain

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 52

Top Venues

This page only lists publications with an associated author ORCID identifier.

Publications

Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J A Barthet, Jacob A Boyer, Riccardo Mezzadra, Matthew G Wereski, David A Tuveson, Ross L Levine, Lee W Jones, Michel Sadelain, Scott W Lowe
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nature aging (2024)
Jae H Park, Maria Lia Palomba, Karlo Perica, Sean M Devlin, Gunjan Shah, Parastoo Dahi, Richard J Lin, Gilles Andre Salles, Michael Scordo, Karthik Nath, Yannis Valtis, Alec Lynch, Elizabeth Cathcart, Honglei Zhang, Heiko Schöder, Doris Leithner, Kelly Liotta, Alina Yu, Kelsey Stocker, Jia Li, Agnish Dey, Leopold Sellner, Reshma Singh, Varsha Sundaresan, Faye Zhao, Jorge Mansilla-Soto, Changhao He, Joel Meyerson, Kinga K Hosszu, Devin McAvoy, Xiuyan Wang, Isabelle Riviere, Michel Sadelain
Calibrated CAR Signaling Enables Low-Dose Therapy in Large B-Cell Lymphoma. Research square (2024)
Anton Dobrin, Pieter L Lindenbergh, Yuzhe Shi, Karlo Perica, Hongyao Xie, Nayan Jain, Andrew Chow, Jedd D Wolchok, Taha Merghoub, Michel Sadelain, Mohamad Hamieh
Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies. Nature cancer 5 (5) (2024)
Karen E Martin, Quirin Hammer, Karlo Perica, Michel Sadelain, Karl-Johan Malmberg
Engineering immune-evasive allogeneic cellular immunotherapies. Nature reviews. Immunology 24 (9) (2024)
Anton Dobrin, Pieter L Lindenbergh, Yuzhe Shi, Karlo Perica, Hongyao Xie, Nayan Jain, Andrew Chow, Jedd D Wolchok, Taha Merghoub, Michel Sadelain, Mohamad Hamieh
Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies. Nature cancer (2024)
Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J A Barthet, Jacob A Boyer, Riccardo Mezzadra, Matthew G Wereski, David A Tuveson, Ross L Levine, Lee W Jones, Michel Sadelain, Scott W Lowe
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nature aging 4 (3) (2024)
Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J A Barthet, Jacob A Boyer, Riccardo Mezzadra, Matthew G Wereski, David A Tuveson, Ross L Levine, Lee W Jones, Michel Sadelain, Scott W Lowe
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nature aging (2024)
Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J A Barthet, Jacob A Boyer, Riccardo Mezzadra, Matthew G Wereski, David A Tuveson, Ross L Levine, Lee W Jones, Michel Sadelain, Scott W Lowe
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nature aging 4 (3) (2024)
Jae H Park, Maria Lia Palomba, Karlo Perica, Sean M Devlin, Gunjan Shah, Parastoo Dahi, Richard J Lin, Gilles Andre Salles, Michael Scordo, Karthik Nath, Yannis Valtis, Alec Lynch, Elizabeth Cathcart, Honglei Zhang, Heiko Schöder, Doris Leithner, Kelly Liotta, Alina Yu, Kelsey Stocker, Jia Li, Agnish Dey, Leopold Sellner, Reshma Singh, Varsha Sundaresan, Faye Zhao, Jorge Mansilla-Soto, Changhao He, Joel Meyerson, Kinga K Hosszu, Devin McAvoy, Xiuyan Wang, Isabelle Riviere, Michel Sadelain
Calibrated CAR Signaling Enables Low-Dose Therapy in Large B-Cell Lymphoma. Research square (2024)
Sjoukje J C van der Stegan, Pieter L Lindenbergh, Roseanna M Petrovic, Hongyao Xie, Mame P Diop, Vera Alexeeva, Yuzhe Shi, Jorge Mansilla-Soto, Mohamad Hamieh, Justin Eyquem, Annalisa Cabriolu, Xiuyan Wang, Ramzey Abujarour, Tom T Lee, Raedun Clarke, Bahram Valamehr, Maria Themeli, Isabelle Riviere, Michel Sadelain
Author Correction: Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells. Nature biomedical engineering (2024)
Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J A Barthet, Jacob A Boyer, Riccardo Mezzadra, Matthew G Wereski, David A Tuveson, Ross L Levine, Lee W Jones, Michel Sadelain, Scott W Lowe
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nature aging 4 (3) (2024)
Fei Yi, Tal Cohen, Natalie Zimmerman, Friederike Dündar, Paul Zumbo, Razan Eltilib, Erica J Brophy, Hannah Arkin, Judith Feucht, Michael V Gormally, Christopher S Hackett, Korbinian N Kropp, Iñaki Etxeberría, Smita S Chandran, Jae H Park, Katharine C Hsu, Michel Sadelain, Doron Betel, Christopher A Klebanoff
CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit. bioRxiv : the preprint server for biology (2024)
Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J A Barthet, Jacob A Boyer, Riccardo Mezzadra, Matthew G Wereski, David A Tuveson, Ross L Levine, Lee W Jones, Michel Sadelain, Scott W Lowe
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nature aging (2024)
Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J A Barthet, Jacob A Boyer, Riccardo Mezzadra, Matthew G Wereski, David A Tuveson, Ross L Levine, Lee W Jones, Michel Sadelain, Scott W Lowe
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nature aging 4 (3) (2024)
Anton Dobrin, Pieter L Lindenbergh, Yuzhe Shi, Karlo Perica, Hongyao Xie, Nayan Jain, Andrew Chow, Jedd D Wolchok, Taha Merghoub, Michel Sadelain, Mohamad Hamieh
Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies. Nature cancer 5 (5) (2024)
Fei Yi, Tal Cohen, Natalie Zimmerman, Friederike Dündar, Paul Zumbo, Razan Eltilib, Erica J Brophy, Hannah Arkin, Judith Feucht, Michael V Gormally, Christopher S Hackett, Korbinian N Kropp, Iñaki Etxeberría, Smita S Chandran, Jae H Park, Katharine C Hsu, Michel Sadelain, Doron Betel, Christopher A Klebanoff
CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit. bioRxiv : the preprint server for biology (2024)
Fei Yi, Tal Cohen, Natalie Zimmerman, Friederike Dündar, Paul Zumbo, Razan Eltilib, Erica J Brophy, Hannah Arkin, Judith Feucht, Michael V Gormally, Christopher S Hackett, Korbinian N Kropp, Iñaki Etxeberría, Smita S Chandran, Jae H Park, Katharine C Hsu, Michel Sadelain, Doron Betel, Christopher A Klebanoff
CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit. bioRxiv : the preprint server for biology (2024)
Corina Amor, Inés Fernández-Maestre, Saria Chowdhury, Yu-Jui Ho, Sandeep Nadella, Courtenay Graham, Sebastian E Carrasco, Emmanuella Nnuji-John, Judith Feucht, Clemens Hinterleitner, Valentin J A Barthet, Jacob A Boyer, Riccardo Mezzadra, Matthew G Wereski, David A Tuveson, Ross L Levine, Lee W Jones, Michel Sadelain, Scott W Lowe
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nature aging 4 (3) (2024)
Karen E Martin, Quirin Hammer, Karlo Perica, Michel Sadelain, Karl-Johan Malmberg
Engineering immune-evasive allogeneic cellular immunotherapies. Nature reviews. Immunology (2024)
Anton Dobrin, Pieter L Lindenbergh, Yuzhe Shi, Karlo Perica, Hongyao Xie, Nayan Jain, Andrew Chow, Jedd D Wolchok, Taha Merghoub, Michel Sadelain, Mohamad Hamieh
Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies. Nature cancer (2024)
Nayan Jain, Zeguo Zhao, Judith Feucht, Richard P Koche, Archana Iyer, Anton Dobrin, Jorge Mansilla-Soto, Julie L Yang, Yingqian Ada Zhan, Michael Lopez, Gertrude Gunset, Michel Sadelain
TET2 guards against unchecked BATF3-induced CAR T cell expansion. Nature 615 (7951) (2023)
Nayan Jain, Zeguo Zhao, Judith Feucht, Richard P Koche, Archana Iyer, Anton Dobrin, Jorge Mansilla-Soto, Julie L Yang, Yingqian Ada Zhan, Michael Lopez, Gertrude Gunset, Michel Sadelain
TET2 guards against unchecked BATF3-induced CAR T cell expansion. Nature (2023)
Nayan Jain, Zeguo Zhao, Judith Feucht, Richard P Koche, Archana Iyer, Anton Dobrin, Jorge Mansilla-Soto, Julie L Yang, Yingqian Ada Zhan, Michael Lopez, Gertrude Gunset, Michel Sadelain
TET2 guards against unchecked BATF3-induced CAR T cell expansion. Nature 615 (7951) (2023)
Changhao He, Jorge Mansilla-Soto, Nandish Khanra, Mohamad Hamieh, Victor Bustos, Alice J Paquette, Andreina Garcia Angus, Derek M Shore, William J Rice, George Khelashvili, Michel Sadelain, Joel R Meyerson
CD19 CAR antigen engagement mechanisms and affinity tuning. Science immunology 8 (81) (2023)
Luis A Rojas, Zachary Sethna, Kevin C Soares, Cristina Olcese, Nan Pang, Erin Patterson, Jayon Lihm, Nicholas Ceglia, Pablo Guasp, Alexander Chu, Rebecca Yu, Adrienne Kaya Chandra, Theresa Waters, Jennifer Ruan, Masataka Amisaki, Abderezak Zebboudj, Zagaa Odgerel, George Payne, Evelyna Derhovanessian, Felicitas Müller, Ina Rhee, Mahesh Yadav, Anton Dobrin, Michel Sadelain, Marta Łuksza, Noah A Cohen, Laura Tang, Olca Basturk, Mithat Gönen, Seth Katz, Richard Kinh Do, Andrew S Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M Varghese, Elizabeth Won, Avni Desai, Alice C Wei, Michael I D'Angelica, T Peter Kingham, Ira Mellman, Taha Merghoub, Jedd D Wolchok, Uğur Şahin, Özlem Türeci, Benjamin D Greenbaum, William R Jarnagin, Jeffrey Drebin, Eileen M O'Reilly, Vinod P Balachandran
Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer. Nature (2023)
Zeguo Zhao, Michel Sadelain
CAR T cell design: approaching the elusive AND-gate. Cell research (2023)
Luis A Rojas, Zachary Sethna, Kevin C Soares, Cristina Olcese, Nan Pang, Erin Patterson, Jayon Lihm, Nicholas Ceglia, Pablo Guasp, Alexander Chu, Rebecca Yu, Adrienne Kaya Chandra, Theresa Waters, Jennifer Ruan, Masataka Amisaki, Abderezak Zebboudj, Zagaa Odgerel, George Payne, Evelyna Derhovanessian, Felicitas Müller, Ina Rhee, Mahesh Yadav, Anton Dobrin, Michel Sadelain, Marta Łuksza, Noah A Cohen, Laura Tang, Olca Basturk, Mithat Gönen, Seth Katz, Richard Kinh Do, Andrew S Epstein, Parisa Momtaz, Wungki Park, Ryan Sugarman, Anna M Varghese, Elizabeth Won, Avni Desai, Alice C Wei, Michael I D'Angelica, T Peter Kingham, Ira Mellman, Taha Merghoub, Jedd D Wolchok, Uğur Şahin, Özlem Türeci, Benjamin D Greenbaum, William R Jarnagin, Jeffrey Drebin, Eileen M O'Reilly, Vinod P Balachandran
Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer. Nature (2023)
Changhao He, Jorge Mansilla-Soto, Nandish Khanra, Mohamad Hamieh, Victor Bustos, Alice J Paquette, Andreina Garcia Angus, Derek M Shore, William J Rice, George Khelashvili, Michel Sadelain, Joel R Meyerson
CD19 CAR antigen engagement mechanisms and affinity tuning. Science immunology 8 (81) (2023)
Ashlesha Odak, Han Yuan, Judith Feucht, Vito Adrian Cantu, Jorge Mansilla-Soto, Friederike Kogel, Justin Eyquem, John K Everett, Frederic D Bushman, Christina S Leslie, Michel Sadelain
Novel extragenic genomic safe harbors for precise therapeutic T cell engineering. Blood (2023)
Ashlesha Odak, Han Yuan, Judith Feucht, Vito Adrian Cantu, Jorge Mansilla-Soto, Friederike Kogel, Justin Eyquem, John K Everett, Frederic D Bushman, Christina S Leslie, Michel Sadelain
Novel extragenic genomic safe harbors for precise therapeutic T cell engineering. Blood (2023)
Nayan Jain, Zeguo Zhao, Judith Feucht, Richard P Koche, Archana Iyer, Anton Dobrin, Jorge Mansilla-Soto, Julie L Yang, Yingqian Ada Zhan, Michael Lopez, Gertrude Gunset, Michel Sadelain
TET2 guards against unchecked BATF3-induced CAR T cell expansion. Nature 615 (7951) (2023)
Changhao He, Jorge Mansilla-Soto, Nandish Khanra, Mohamad Hamieh, Victor Bustos, Alice J Paquette, Andreina Garcia Angus, Derek M Shore, William J Rice, George Khelashvili, Michel Sadelain, Joel R Meyerson
CD19 CAR antigen engagement mechanisms and affinity tuning. Science immunology 8 (81) (2023)
Mohamad Hamieh, Jorge Mansilla-Soto, Isabelle Rivière, Michel Sadelain
Programming CAR T Cell Tumor Recognition: Tuned Antigen Sensing and Logic Gating. Cancer discovery (2023)
Nayan Jain, Zeguo Zhao, Richard P Koche, Chenling A Xu, Yosi Gozlan, Antonino Montalbano, David Brocks, Michael Lopez, Anton Dobrin, Yuzhe Shi, Gertrude Gunset, Theodoros Giavridis, Michel Sadelain
Disruption of SUV39H1-mediated H3K9 methylation sustains CAR T cell function. Cancer discovery (2023)
Jae H Park, Karthik Nath, Sean M Devlin, Craig S Sauter, Maria Lia Palomba, Gunjan Shah, Parastoo Dahi, Richard J Lin, Michael Scordo, Miguel-Ángel Perales, Roni Shouval, Ana Alarcon Tomas, Elizabeth Cathcart, Elena Mead, Bianca D Santomasso, Andrei I Holodny, Renier J Brentjens, Isabelle Riviere, Michel Sadelain
CD19 CAR T-cell therapy and prophylactic anakinra in relapsed or refractory lymphoma: phase 2 trial interim results. Nature medicine (2023)
Nayan Jain, Zeguo Zhao, Judith Feucht, Richard P Koche, Archana Iyer, Anton Dobrin, Jorge Mansilla-Soto, Julie L Yang, Yingqian Ada Zhan, Michael Lopez, Gertrude Gunset, Michel Sadelain
TET2 guards against unchecked BATF3-induced CAR T cell expansion. Nature (2023)
Changhao He, Jorge Mansilla-Soto, Nandish Khanra, Mohamad Hamieh, Victor Bustos, Alice J Paquette, Andreina Garcia Angus, Derek M Shore, William J Rice, George Khelashvili, Michel Sadelain, Joel R Meyerson
CD19 CAR antigen engagement mechanisms and affinity tuning. Science immunology 8 (81) (2023)
Jorge Mansilla-Soto, Justin Eyquem, Sascha Haubner, Mohamad Hamieh, Judith Feucht, Noémie Paillon, Andrés Ernesto Zucchetti, Zhuoning Li, Maria Sjöstrand, Pieter L Lindenbergh, Michelle Saetersmoen, Anton Dobrin, Mathieu Maurin, Archana Iyer, Andreina Garcia Angus, Matthew M Miele, Zeguo Zhao, Theodoros Giavridis, Sjoukje J C van der Stegan, Fella Tamzalit, Isabelle Rivière, Morgan Huse, Ronald C Hendrickson, Claire Hivroz, Michel Sadelain
HLA-independent T cell receptors for targeting tumors with low antigen density. Nature medicine 28 (2) (2022)
Sjoukje J C van der Stegan, Pieter L Lindenbergh, Roseanna M Petrovic, Hongyao Xie, Mame P Diop, Vera Alexeeva, Yuzhe Shi, Jorge Mansilla-Soto, Mohamad Hamieh, Justin Eyquem, Annalisa Cabriolu, Xiuyan Wang, Ramzey Abujarour, Tom T Lee, Raedun Clarke, Bahram Valamehr, Maria Themeli, Isabelle Riviere, Michel Sadelain
Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells. Nature biomedical engineering 6 (11) (2022)
Farid Boulad, Aurelio Maggio, Xiuyan Wang, Paolo Moi, Santina Acuto, Friederike Kogel, Chayamon Takpradit, Susan Prockop, Jorge Mansilla-Soto, Annalisa Cabriolu, Ashlesha Odak, Jinrong Qu, Keyur Thummar, Fang Du, Lingbo Shen, Simona Raso, Rita Barone, Rosario Di Maggio, Lorella Pitrolo, Antonino Giambona, Maura Mingoia, John K Everett, Pascha Hokama, Aoife M Roche, Vito Adrian Cantu, Hriju Adhikari, Shantan Reddy, Eric Bouhassira, Narla Mohandas, Frederic D Bushman, Isabelle Rivière, Michel Sadelain
Lentiviral globin gene therapy with reduced-intensity conditioning in adults with β-thalassemia: a phase 1 trial. Nature medicine 28 (1) (2022)
Melody Smith, Anqi Dai, Guido Ghilardi, Kimberly V Amelsberg, Sean M Devlin, Raymone Pajarillo, John B Slingerland, Silvia Beghi, Pamela S Herrera, Paul Giardina, Annelie Clurman, Emmanuel Dwomoh, Gabriel Armijo, Antonio L C Gomes, Eric R Littmann, Jonas Schluter, Emily Fontana, Ying Taur, Jae H Park, Maria Lia Palomba, Elizabeth Halton, Josel Ruiz, Tania Jain, Martina Pennisi, Aishat Olaide Afuye, Miguel-Ángel Perales, Craig W Freyer, Alfred Garfall, Shannon Gier, Sunita Nasta, Daniel Landsburg, James Gerson, Jakub Svoboda, Justin Cross, Elise A Chong, Sergio Giralt, Saar I Gill, Isabelle Riviere, David L Porter, Stephen J Schuster, Michel Sadelain, Noelle Frey, Renier J Brentjens, Carl H June, Eric G Pamer, Jonathan U Peled, Andrea Facciabene, Marcel R M van den Brink, Marco Ruella
Author Correction: Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy. Nature medicine (2022)
Marta Łuksza, Zachary M Sethna, Luis A Rojas, Jayon Lihm, Barbara Bravi, Yuval Elhanati, Kevin C Soares, Masataka Amisaki, Anton Dobrin, David Hoyos, Pablo Guasp, Abderezak Zebboudj, Rebecca Yu, Adrienne Kaya Chandra, Theresa Waters, Zagaa Odgerel, Joanne Leung, Rajya Kappagantula, Alvin P Makohon-Moore, Amber Johns, Anthony Gill, Mathieu Gigoux, Jedd D Wolchok, Taha Merghoub, Michel Sadelain, Erin Patterson, Remi Monasson, Thierry Mora, Aleksandra M Walczak, Simona Cocco, Christine A Iacobuzio-Donahue, Benjamin D Greenbaum, Vinod P Balachandran
Neoantigen quality predicts immunoediting in survivors of pancreatic cancer. Nature 606 (7913) (2022)
Melody Smith, Anqi Dai, Guido Ghilardi, Kimberly V Amelsberg, Sean M Devlin, Raymone Pajarillo, John B Slingerland, Silvia Beghi, Pamela S Herrera, Paul Giardina, Annelie Clurman, Emmanuel Dwomoh, Gabriel Armijo, Antonio L C Gomes, Eric R Littmann, Jonas Schluter, Emily Fontana, Ying Taur, Jae H Park, Maria Lia Palomba, Elizabeth Halton, Josel Ruiz, Tania Jain, Martina Pennisi, Aishat Olaide Afuye, Miguel-Ángel Perales, Craig W Freyer, Alfred Garfall, Shannon Gier, Sunita Nasta, Daniel Landsburg, James Gerson, Jakub Svoboda, Justin Cross, Elise A Chong, Sergio Giralt, Saar I Gill, Isabelle Riviere, David L Porter, Stephen J Schuster, Michel Sadelain, Noelle Frey, Renier J Brentjens, Carl H June, Eric G Pamer, Jonathan U Peled, Andrea Facciabene, Marcel R M van den Brink, Marco Ruella
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy. Nature medicine 28 (4) (2022)
Prasad S Adusumilli, Marjorie G Zauderer, Isabelle Rivière, Stephen B Solomon, Valerie W Rusch, Roisin E O'Cearbhaill, Amy Zhu, Waseem Cheema, Navin K Chintala, Elizabeth Halton, John Pineda, Rocio Perez-Johnston, Kay See Tan, Bobby Daly, Jose A Araujo Filho, Daniel Ngai, Erin McGee, Alain Vincent, Claudia Diamonte, Jennifer L Sauter, Shanu Modi, Devanjan Sikder, Brigitte Senechal, Xiuyan Wang, William D Travis, Mithat Gönen, Charles M Rudin, Renier J Brentjens, David R Jones, Michel Sadelain
A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti-PD-1 Agent Pembrolizumab. Cancer discovery 11 (11) (2021)
Minggang Zhang, Zeguo Zhao, Yuri Pritykin, Margaret Hannum, Andrew C Scott, Fengshen Kuo, Viraj R Sanghvi, Timothy A Chan, Venkatraman Seshan, Hans-Guido Wendel, Andrea Schietinger, Michel Sadelain, Morgan Huse
Ectopic activation of the miR-200c-EpCAM axis enhances antitumor T cell responses in models of adoptive cell therapy. Science translational medicine 13 (611) (2021)
Afroditi Katsarou, Maria Sjöstrand, Jyoti Naik, Jorge Mansilla-Soto, Dionysia Kefala, Georgios Kladis, Alexandros Nianias, Ruud Ruiter, Renée Poels, Irene Sarkar, Yash R Patankar, Elena Merino, Rogier M Reijmers, Kristine A Frerichs, Huipin Yuan, Joost D de Bruijn, Dina Stroopinsky, David Avigan, Niels W C J van de Donk, Sonja Zweegman, Tuna Mutis, Michel Sadelain, Richard W J Groen, Maria Themeli
Combining a CAR and a chimeric costimulatory receptor enhances T cell sensitivity to low antigen density and promotes persistence. Science translational medicine 13 (623) (2021)
Kitsada Wudhikarn, Jessica R Flynn, Isabelle Rivière, Mithat Gönen, Xiuyan Wang, Brigitte Senechal, Kevin J Curran, Mikhail Roshal, Peter G Maslak, Mark Blaine Geyer, Elizabeth F Halton, Claudia Diamonte, Marco L Davila, Michel Sadelain, Renier J Brentjens, Jae H Park
Interventions and outcomes of adult patients with B-ALL progressing after CD19 chimeric antigen receptor T-cell therapy. Blood 138 (7) (2021)
Katrin Mestermann, Theodoros Giavridis, Justus Weber, Julian Rydzek, Silke Frenz, Thomas Nerreter, Andreas Mades, Michel Sadelain, Hermann Einsele, Michael Hudecek
The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells. Science translational medicine 11 (499) (2020)
Kevin J Curran, Steven P Margossian, Nancy A Kernan, Lewis B Silverman, David A Williams, Neerav Shukla, Rachel Kobos, Christopher J Forlenza, Peter Steinherz, Susan Prockop, Farid Boulad, Barbara Spitzer, Maria I Cancio, Jaap-Jan Boelens, Andrew L Kung, Yasmin Khakoo, Victoria Szenes, Jae H Park, Craig S Sauter, Glenn Heller, Xiuyan Wang, Brigitte Senechal, Richard J O'Reilly, Isabelle Riviere, Michel Sadelain, Renier J Brentjens
Toxicity and response after CD19-specific CAR T-cell therapy in pediatric/young adult relapsed/refractory B-ALL. Blood 134 (26) (2020)
Craig S Sauter, Brigitte Senechal, Isabelle Rivière, Ai Ni, Yvette Bernal, Xiuyan Wang, Terence Purdon, Malloury Hall, Ashvin N Singh, Victoria Z Szenes, Sarah Yoo, Ahmet Dogan, Yongzeng Wang, Craig H Moskowitz, Sergio A Giralt, Matthew J Matasar, Miguel-Angel Perales, Kevin J Curran, Jae Park, Michel Sadelain, Renier J Brentjens
CD19 CAR T cells following autologous transplantation in poor-risk relapsed and refractory B-cell non-Hodgkin lymphoma. Blood 134 (7) (2019)
Cynthia E Dunbar, Katherine A High, J Keith Joung, Donald B Kohn, Keiya Ozawa, Michel Sadelain
Gene therapy comes of age. Science (New York, N.Y.) 359 (6372) (2018)
Judith Feucht, Jie Sun, Justin Eyquem, Yu-Jui Ho, Zeguo Zhao, Josef Leibold, Anton Dobrin, Annalisa Cabriolu, Mohamad Hamieh, Michel Sadelain
Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency. Nature medicine 25 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Michel Sadelain