Association between nitric oxide synthase T-786C genetic polymorphism and chronic kidney disease: Meta-analysis incorporating trial sequential analysis.

Po-Jen HsiaoChih-Chien ChiuDung-Jang TsaiPi-Shao KoYing-Kai ChenHao ChengWen SuKuo-Cheng LuSui-Lung Su

Published in: PloS one (2021)

eNOS T-786C genetic polymorphism was of conclusive significance in the association with CKD among Asians in our meta-analysis. Our case-control samples play a decisive role in changing conclusions from indefinite to definite.

Keyphrases

case control
nitric oxide synthase
chronic kidney disease
systematic review
nitric oxide
meta analyses
end stage renal disease
genome wide
study protocol
copy number
randomized controlled trial
endothelial cells
dna methylation
phase iii