Sphingosine kinase 1 regulates lysyl oxidase through STAT3 in hyperoxia-mediated neonatal lung injury.

Alison W HaTao BaiDavid L EbenezerTanvi SethiTara SudhadeviLizar Ace MangioSteven GarzonGloria S PryhuberViswanathan NatarajanAnantha Harijith

Published in: Thorax (2021)

HO-induced SPHK1/S1P signalling axis plays a critical role in transcriptional regulation of LOX expression via SPNS2, S1P1 and STAT3 in lung endothelium.

Keyphrases

cell proliferation
poor prognosis
high glucose
nitric oxide
diabetic rats
drug induced
protein kinase
binding protein
tyrosine kinase
pi k akt
long non coding rna