Novel probiotic yeast from Miso promotes regulatory dendritic cell IL-10 production and attenuates DSS-induced colitis in mice.

Yoshikiyo OkadaYoshikazu TsuzukiNao SugiharaShin NishiiNaoki ShibuyaAkinori MizoguchiSuguru ItohRina TanemotoKenichi InabaYoshinori HanawaKazuki HoriuchiAkinori WadaMasaaki HigashiyamaChikako WatanabeChie KuriharaShunsuke KomotoKengo TomitaSoichiro MiuraRyota Hokari

Published in: Journal of gastroenterology (2021)

Strain I-6 induced phenotypic changes in intestinal CD11c+ DCs characterized by high IL-10 production and exerted strong anti-inflammatory effects on DSS-induced colitis. Traditional Japanese fermented foods may be a valuable source of probiotic yeasts for effective IBD therapy and treatment.

Keyphrases

dendritic cells
anti inflammatory
lactic acid
saccharomyces cerevisiae
high glucose
bacillus subtilis
regulatory t cells
diabetic rats
transcription factor
oxidative stress
drug induced
immune response
endothelial cells
adipose tissue
insulin resistance
nk cells
cell wall