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miR-361-5p as a promising qRT-PCR internal control for tumor and normal breast tissues.

Sogol GhanbariAdel SalimiSaeid RahmaniNahid NafissiAli Sharifi-ZarchiSeyed Javad Mowal
Published in: PloS one (2021)
miRNA-Seq data is a great source to discover stable ICs. Our results demonstrated that hsa-miR-361-5p is a highly stable miRNA in tumor and non-tumor breast tissue and we recommend it as a suitable reference gene for miRNA expression studies in breast cancer. Additionally, although hsa-miR-16-5p is a commonly used IC, it's not a suitable one for breast cancer studies.
Keyphrases
  • genome wide
  • poor prognosis
  • gene expression
  • rna seq
  • case control
  • dna methylation
  • electronic health record
  • big data
  • binding protein
  • deep learning