Cost-effectiveness analysis of reflex testing for Lynch syndrome in women with endometrial cancer in the UK setting.
Tristan M SnowsillNeil A J RyanEmma J CrosbieIan M FraylingD Gareth EvansChris J HydePublished in: PloS one (2019)
Testing for Lynch syndrome in younger women with endometrial cancer using MMR immunohistochemistry and MLH1 methylation testing may be cost-effective. Age cut-offs may be controversial and adversely affect implementation.