Trends in HOMA-IR values among South Korean adolescents from 2007-2010 to 2019-2020: a sex-, age-, and weight status-specific analysis.

Su Jin Kim Kyungchul SongMyeongseob LeeJunghwan SuhHyun-Wook Chae Ho Seong Kim Ahreum Kwon

Published in: International journal of obesity (2005) (2023)

HOMA-IR values should be interpreted considering sex, weight status, and pubertal stages. In particular, during the pubertal period, insulin resistance (IR) can coexist not only due to weight-related factors but also as a result of the distinct hormonal changes characteristic of puberty. Over the 10-year period, the mean HOMA-IR values increased in the group with overweight/obesity during puberty and post-puberty, highlighting the need for active intervention to prevent metabolic complications in adolescents with overweight/obesity.

Keyphrases

weight loss
weight gain
physical activity
insulin resistance
body mass index
young adults
metabolic syndrome
polycystic ovary syndrome
high fat diet induced
type diabetes
randomized controlled trial
adipose tissue
glycemic control
skeletal muscle
high fat diet
risk factors
body weight