Five-year outcomes for patients sustaining severe fractures of the lower limb from the Wound Healing in Surgery for Trauma (WHIST) trial.
Matthew Lee CostaJuul AchtenRuth KnightMarta CampolierM Sofia MassaPublished in: The bone & joint journal (2024)
We found no evidence of a difference in disability ratings between NPWT compared with standard wound dressings in the five years following the surgical treatment of a complex fracture of the lower limb. Patients in both groups reported high levels of persistent disability and reduced quality of life, with little evidence of improvement during this time.
Keyphrases
- lower limb
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- multiple sclerosis
- peritoneal dialysis
- prognostic factors
- minimally invasive
- randomized controlled trial
- patient reported outcomes
- early onset
- adipose tissue
- study protocol
- coronary artery bypass
- skeletal muscle
- acute coronary syndrome
- phase ii
- drug induced
- glycemic control
- surgical site infection