Tyrphostin AG17 inhibits adipocyte differentiation in vivo and in vitro.

Alberto CamachoJuan Carlos Segoviano-RamírezAdriana Sánchez-GarciaJose de Jesus Herrera-de la RosaJaime García-JuarezCarlos Alberto Hernandez-PuenteGeovana Calvo-AnguianoSergio Rodolfo Maltos-UroAlejandra OlguinGabriel Gojon-RomanillosGabriel Gojon-ZorrillaRocio Ortiz-Lopez

Published in: Lipids in health and disease (2018)

T-AG17 promotes adipocyte apoptosis in vivo and is an effective modulator of adipocyte differentiation and WAT hypertrophy in vitro and in vivo. Therefore, T-AG17 may be useful as a pharmacological obesity treatment.

Keyphrases

insulin resistance
adipose tissue
quantum dots
fatty acid
highly efficient
metabolic syndrome
visible light
skeletal muscle
high fat diet induced
type diabetes
oxidative stress
endoplasmic reticulum stress
cell death
weight loss
cell cycle arrest
weight gain
physical activity
body mass index