Genome-Wide Association Study of Peripheral Artery Disease.

Natalie R van ZuydamAlexander StibyMoustafa Abdalla Erin AustinStela McLachlanEfthymia VlachopoulouEmma Ahlqvist Chen Di Liao Erkka Valo Carol M ForsblomAnubha MahajanNeil R RobertsonNigel William Rayner Eero Lindholm Juha Sinisalo Markus Perola Milla Kallio Emily WeissJackie PriceAndrew D PatersonBarbara KleinVeikko V Salomaa Colin Neil Alexander PalmerPer-Henrik GroopLeif GroopMark I McCarthy Mariza de AndradeAndrew P MorrisJemma C Hopewell Helen Martina Colhoun Iftikhar J Kullonull null

Published in: Circulation. Genomic and precision medicine (2021)

Our analyses confirm the published genetic associations with PAD and identify novel variants that may influence susceptibility to PAD in the context of diabetes or smoking status.

Keyphrases

genome wide association study
peripheral artery disease
copy number
type diabetes
cardiovascular disease
genome wide
smoking cessation
glycemic control
systematic review
randomized controlled trial
dna methylation
meta analyses
insulin resistance