Assessment of the influence of Fc-γ receptor polymorphisms on biologics' pharmacokinetics in Tunisian rheumatoid arthritis patients.
Ines MahmoudMyriam MoallaAicha Ben TekayaRim CharfiLeila RouachedSelma BoudenRawdha TekayaOlfa SaidaneLeila AbdelmoulaImen SfarPublished in: British journal of clinical pharmacology (2023)
Our work supports the hypothesis of an impact of FcgR single nucleotide polymorphisms on biologics' immunogenicity, particularly FcgR R131H polymorphism, but further studies with larger cohorts need to be undertaken to confirm these results.