CSF SerpinA1 in Creutzfeldt-Jakob disease and frontotemporal lobar degeneration.
Markus OttoSteffen HalbgebauerPetra SteinackerSarah Anderl-StraubBarbara PolischiAlbert C LudolphSabina CapellariPiero ParchiMarkus OttoPublished in: Annals of clinical and translational neurology (2020)
CJD linked to PrPSc type 1 and FTLD show a differential upregulation and post-translational modifications of CSF SerpinA1. Further studies are needed to clarify whether these findings may reflect a common, albeit disease-specific, pathogenetic mechanism related to neurodegeneration.
Keyphrases