Upregulation of BUB1B, CCNB1, CDC7, CDC20, and MCM3 in Tumor Tissues Predicted Worse Overall Survival and Disease-Free Survival in Hepatocellular Carcinoma Patients.

Liping Zhuang Zongguo Yang ZhiQiang Meng

Published in: BioMed research international (2018)

Correlated with advanced histologic grade and/or vascular invasion, upregulation of BUB1B, CCNB1, CDC7, CDC20, and MCM3 in HCC tissues predicted worse OS and DFS in HCC patients. These genes could be novel therapeutic targets for HCC treatment.

Keyphrases

end stage renal disease
free survival
chronic kidney disease
newly diagnosed
cell cycle
gene expression
peritoneal dialysis
cell proliferation
poor prognosis
signaling pathway
genome wide
long non coding rna
patient reported