Untargeted metabolomics identifies a plasma sphingolipid-related signature associated with lifestyle intervention in prepubertal children with obesity.

M J Leal-WittM Ramon-KrauelS SaminoM LlobetD CuadrasJ C Jimenez-ChillaronO YanesCarles Lerin

Published in: International journal of obesity (2005) (2017)

Decreased circulating sphingolipid-related metabolites were associated with lifestyle intervention in prepubertal children with obesity, and correlated to improvements in HbA1c.

Keyphrases

metabolic syndrome
weight loss
randomized controlled trial
insulin resistance
young adults
mass spectrometry
type diabetes
high fat diet induced
weight gain
physical activity
cardiovascular disease
ms ms
adipose tissue
skeletal muscle
dna methylation
growth hormone