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Age at introduction to complementary solid food and food allergy and sensitization: A systematic review and meta-analysis.

John A BurgessShyamali C DharmageKatrina AllenJennifer J KoplinVanessa Garcia-LarsenRobert J BoyleNilakshi T WaidyatillakeCaroline Jane Lodge
Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2019)
We found no evidence from observational studies that introducing solids before 4 months protected against food allergy, but there was evidence for protection against food sensitization. From RCTs, introducing egg from 4 to 6 months and peanut from 4 to 11 months reduced the risk of egg allergy, peanut allergy and egg sensitization. PROSPERO systematic review registry (CRD42016033473).
Keyphrases
  • systematic review
  • meta analyses
  • human health
  • atopic dermatitis
  • infectious diseases
  • randomized controlled trial
  • risk assessment
  • climate change