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Composite Plot for Visualizing Aminotransferase and Bilirubin Changes in Clinical Trials of Subjects with Abnormal Baseline Values.

Bereket TesfaldetTejas PatelMinjun ChenFrank PucinoLilliam RosarioPaul HayashiEileen Navarro Almario
Published in: Drug safety (2024)
For studies in subjects with abnormal baseline values, the composite plot has potential application in the assessment of beneficial and concerning on-treatment modifications in liver test values in reference to the individual subject's baseline and population threshold values.
Keyphrases
  • clinical trial
  • randomized controlled trial
  • open label
  • combination therapy
  • human health
  • phase ii
  • living cells
  • single molecule
  • phase iii