One-Pot Synthesis of Core Structure of Shewanelline C Using an Azidoindoline.
Toshiki YamashiroKeisuke TokushigeTakumi AbePublished in: The Journal of organic chemistry (2023)
The unprecedented synthesis of the indolines bearing N3-quinazolin-2,4-dione moiety using an AZIN is reported. The concise synthesis features the tandem Staudinger/chemo-selective aza-Wittig/cyclization sequence of AZINs with isatoic anhydride by a one-pot protocol.