Anti-PD-1 for the treatment of advanced cutaneous squamous cell carcinoma in elderly patients: a French multicenter retrospective survey.
Quentin SamaranRomain SamaranErnestine FerreiraNaeda HaddadAntoine FottorinoHervé MaillardBrigitte DrenoNicolas MeyerDavid AzriaEve MaubecCaroline Gaudy-MarquesteNicolas MolinariPierre-Emmanuel StoebnerOlivier DereurePublished in: Journal of cancer research and clinical oncology (2022)
In this particular subset of acSCC patients PD-1 inhibitors obtain results similar to those obtained in younger populations included in pivotal clinical trials, with acceptable safety. A specific oncogeriatric evaluation at treatment initiation and during follow-up appears important in this setting most notably to help manage toxicity.