Lipid emulsion, but not propofol, induces skeletal muscle damage and lipid peroxidation.

Tomohiro ChakiNaoyuki HirataYusuke YoshikawaShunsuke TachibanaYasuyuki TokinagaMichiaki Yamakage

Published in: Journal of anesthesia (2019)

Lipofundin induces skeletal muscle damage via lipid peroxidation, and 1% propofol (Maruishi) conversely suppresses the muscle damage via antioxidant effects.

Keyphrases

skeletal muscle
oxidative stress
insulin resistance
fatty acid
signaling pathway
type diabetes
metabolic syndrome
adipose tissue