Clinical Characterization and Immunosuppressive Regulation of CD161 (KLRB1) in Glioma through 916 Samples.

Di WangWenhua FanFan WuZhongfang ShiZhiliang WangMingchen YuYou ZhaiYuanhao ChangChangqing PanGuanzhang LiUlf Dietrich Kahlert Wei Zhang

Published in: Cancer science (2021)

The expression of CD161 was closely related to the pathology and molecular pathology of glioma. Meanwhile, CD161 promoted the progression and evolution of gliomas through its unique effect on T cell dysfunction. Thus, CD161 is a promising novel target for immunotherapeutic strategies of glioma.

Keyphrases

nk cells
poor prognosis
oxidative stress
high grade
long non coding rna
drug induced