Nocturnal blood pressure dipping as a marker of endothelial function and subclinical atherosclerosis in pediatric-onset systemic lupus erythematosus.
Joyce C ChangRui XiaoKevin E MeyersLaura Mercer-RosaShobha S NatarajanPamela F WeissAndrea M KnightPublished in: Arthritis research & therapy (2020)
In a pSLE cohort with low disease activity, isolated nocturnal BP non-dipping is prevalent and associated with endothelial dysfunction and atherosclerotic changes. In addition to hypertension assessment, ABPM has a promising role in risk stratification and understanding heterogeneous mechanisms of cardiovascular disease in pSLE.
Keyphrases
- blood pressure
- disease activity
- systemic lupus erythematosus
- cardiovascular disease
- rheumatoid arthritis patients
- rheumatoid arthritis
- hypertensive patients
- ankylosing spondylitis
- heart rate
- juvenile idiopathic arthritis
- type diabetes
- blood glucose
- cardiovascular risk factors
- obstructive sleep apnea
- metabolic syndrome
- coronary artery disease
- depressive symptoms
- weight loss
- childhood cancer