Efficacy of topiramate as an add-on therapy in patients with refractory status epilepticus: a short systematic review.
Leonardo Christiaan WellingNícollas Nunes RabeloMarcia Harumy YoshikawaJoão Paulo Motta TellesManoel Jacobsen TeixeiraEberval Gadelha FigueiredoPublished in: Revista Brasileira de terapia intensiva (2021)
Topiramate was effective in terminating refractory status epilepticus, presented relatively low mortality and was well tolerated. Therefore, topiramate could be a good option as a third-line therapy for refractory status epilepticus, but further studies are necessary.