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Conventional versus minimally invasive extra-corporeal circulation in patients undergoing cardiac surgery: A randomized controlled trial (COMICS).

Gianni Davide AngeliniBarnaby C ReevesLucy A CullifordRachel MaishmanChris A RogersKyriakos AnastasiadisPolychronis AntonitsisHelena ArgiriadouThierry CarrelDorothée KellerAndreas LieboldFatma AshkanianiAschraf El-EssawiIngo BreitenbachClinton LloydMark BennettAlex CaleSerdar GünaydinEren GunertemFarouk OueidaIbrahim M YassinCyril SerrickJohn M MurkinVivek RaoMarco MoscarelliIgnazzo CondelloPrakash P PunjabiCha RajakarunaApostolos DeliopoulosDaniel BoneWilliam LansdownNarain MoorjaniSarah Dennis
Published in: Perfusion (2024)
MiECC reduces the relative risk of primary outcome events by about 25%. The risk of other SAEs was similarly reduced. Because the trial terminated early without achieving the target sample size, these potential benefits of MiECC are uncertain.
Keyphrases
  • cardiac surgery
  • minimally invasive
  • patients undergoing
  • acute kidney injury
  • study protocol
  • phase iii
  • clinical trial
  • phase ii
  • robot assisted
  • human health
  • open label
  • randomized controlled trial
  • risk assessment