Genetic polymorphisms in phase II metabolizing enzymes in alcoholic and idiopathic chronic pancreatitis: Indian scenario.

Nidhi SinghSafoora RashidSumaira RashidHem Chandra SatiSurabhi GuptaMeera VaswaniAnoop Saraya

Published in: Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology (2023)

Alcoholics with the null genotype of the GST-T1 gene and the Valine allele of the GST-P1 gene are at a higher risk of developing CP. Thus, genotyping of these genes may serve as an important screening tool for the identification of high-risk groups among alcoholics.

Keyphrases

genome wide
phase ii
genome wide identification
clinical trial
copy number
open label
dna methylation
bioinformatics analysis
transcription factor
high throughput
phase iii
randomized controlled trial
liver injury
double blind
placebo controlled
gene expression
study protocol