Adenosine A3 receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury.

Susan A FarrSalvatore CuzzocreaEmanuela EspositoMichela CampoloMichael L NiehoffTimothy M DoyleDaniela Salvemini

Published in: Journal of neuroinflammation (2020)

Our results provide support for the beneficial effects of small molecule A3AR agonists to mitigate secondary tissue injury and cognitive impairment following TBI.

Keyphrases

traumatic brain injury
small molecule
cognitive impairment
severe traumatic brain injury
bipolar disorder
protein protein
protein kinase
mild traumatic brain injury