Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cell Therapy in Preclinical Models of Sepsis: A Systematic Review and Meta-analysis.

Christine HumUsama TahirShirley H J MeiJosee ChampagneDean A FergussonManoj LaluDuncan J StewartKeith WalleyJohn MarshallClaudia C Dos SantosBrent W WinstonAsher A MendelsonChintan DaveLauralyn McIntyre

Published in: Stem cells translational medicine (2024)

These results demonstrate the efficacy of UC-MSC treatment in preclinical sepsis models and highlight their potential as a therapeutic intervention for septic shock.

Keyphrases

septic shock
cell therapy
mesenchymal stem cells
umbilical cord
bone marrow
stem cells
randomized controlled trial
intensive care unit
acute kidney injury
climate change
combination therapy