A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern.

Nina Urke ErtesvågJulie XiaoFan ZhouSonja LjostveitHelene SandnesSarah LarteyMarianne SævikLena HansenAnders MadsenKristin Greve-Isdahl MohnElisabeth FjelltveitJan Stefan Olofsson Tiong Kit Tan Pramila RijalLisa SchimanskiSiri ØyenKarl Albert BrokstadSusanna J DunachieAnni JämsénWilliam S JamesAdam C HardingHeli HarvalaDung NguyenDavid Robertsnull nullMaria Zambonnull nullAlain Townsendnull nullNina Langeland Rebecca Jane Cox

Published in: Communications medicine (2022)

Overall, HAT provides a surrogate marker for neutralising antibodies, which can be used as a simple inexpensive, rapid test. HAT can be rapidly adaptable to emerging VOC for large-scale evaluation of potentially decreasing vaccine effectiveness.

Keyphrases

sars cov
loop mediated isothermal amplification
randomized controlled trial
systematic review
copy number
respiratory syndrome coronavirus
gene expression