Electroacupuncture improves gout arthritis pain via attenuating ROS-mediated NLRP3 inflammasome overactivation.

Huina WeiBoyu LiuChengyu YinDanyi ZengHuimin NieYuanyuan LiYan TaiXiaofen HeBo-Yi Liu

Published in: Chinese medicine (2023)

Our results demonstrate that EA reduces gout pain possibly through suppressing ROS-mediated NLRP3 inflammasome activation in inflamed ankle joints and TRPV1 upregulation in sensory neurons, supporting EA as a treatment option for gout pain.

Keyphrases

nlrp inflammasome
neuropathic pain
chronic pain
pain management
uric acid
spinal cord
dna damage
signaling pathway
spinal cord injury
rheumatoid arthritis
reactive oxygen species
cell proliferation
metabolic syndrome
poor prognosis
postoperative pain
replacement therapy