Effectiveness of ChAdOx1 nCoV-19 and BBIBP-CorV vaccines against COVID-19-associated hospitalisation and death in the Seychelles infected adult population.

Sylvie Nadine Theresa PoolEmelyn Helen ShroffAgnes ChettyLara LewisYende-Zuma NonhlanhlaSalim S Abdool Karim

Published in: PloS one (2024)

This observational study demonstrated high levels of protection of two doses of two vaccine types against severe outcomes of COVID-19 during the first wave of the pandemic driven by Beta (B.1.351) and Delta (B.1.617.2) variant predominance. One dose of ChAdOx1-nCoV-19 (Covishield SII) was found to be inadequate in protecting the general adult population against hospitalisation and/or death from COVID-19.

Keyphrases

coronavirus disease
sars cov
respiratory syndrome coronavirus
randomized controlled trial
systematic review
type diabetes
early onset
skeletal muscle