Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway.

Shihao XiangKan Chen Ling XuTing WangChuan-Yong Guo

Published in: Drug design, development and therapy (2020)

Bergenin exerts hepatic protection by eliminating ROS, affecting the release of inflammatory factors, and influencing apoptosis- and autophagy-related genes via the PPAR-γ pathway in this model of hepatic IR injury.

Keyphrases

oxidative stress
cell death
endoplasmic reticulum stress
cell cycle arrest
dna damage
signaling pathway
insulin resistance
fatty acid
metabolic syndrome
adipose tissue
skeletal muscle
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