Postponing tumor onset and tumor progression can be achieved by alteration of local tumor immunity.

Yan MeiMingdian WangGuanming LuJiangchao LiLixia PengYanhong LangMingming YangLingbi JiangChangzhi LiLisheng ZhengZhijie LiuDehuan XieLingling GuoBijun HuangMusheng ZengYanxia ShiChao-Nan Qian

Published in: Cancer cell international (2021)

All these findings suggest that immunity levels (characterized by a reduced IL-6 level and intact DC maturation in Fvb.B6 mice) are the key factors affecting tumor onset in a murine mammary cancer model.

Keyphrases

dendritic cells
squamous cell carcinoma
poor prognosis
type diabetes
metabolic syndrome
skeletal muscle
insulin resistance