Response to Brentuximab Vedotin by CD30 Expression in Non-Hodgkin Lymphoma.
Deepa JagadeeshSteve HorwitzNancy L BartlettYoun KimEric JacobsenMadeleine DuvicMeredith LittleWilliam TrepicchioKeenan FentonMatthew OnsumJulie LisanoRanjana AdvaniPublished in: The oncologist (2022)
In this analysis of studies across a range of CD30-expressing lymphomas, CD30 expression alone, as measured by standard IHC, does not predict clinical benefit from BV, making the determination of a threshold level of expression uncertain.