Interleukin-4 increases phagocytosis of necrotic cells by macrophages through scavenger receptor CD36.

Mingzhuang ChenGary TseWing Tak Wong

Published in: Clinical and experimental pharmacology & physiology (2020)

Interleukin-4 can accelerate cell debris clearance by stimulating expression of CD36, which requires downstream STAT6 activation. Its beneficial effects on driving tissue repair and regeneration should be explored in future studies.

Keyphrases

induced apoptosis
stem cells
poor prognosis
cell cycle arrest
single cell
nk cells
cell proliferation
binding protein
current status
oxidative stress
case control
wound healing