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Interleukin-4 increases phagocytosis of necrotic cells by macrophages through scavenger receptor CD36.

Mingzhuang ChenGary TseWing Tak Wong
Published in: Clinical and experimental pharmacology & physiology (2020)
Interleukin-4 can accelerate cell debris clearance by stimulating expression of CD36, which requires downstream STAT6 activation. Its beneficial effects on driving tissue repair and regeneration should be explored in future studies.
Keyphrases
  • induced apoptosis
  • stem cells
  • poor prognosis
  • cell cycle arrest
  • single cell
  • nk cells
  • cell proliferation
  • binding protein
  • current status
  • oxidative stress
  • case control
  • wound healing