Magnetic resonance elastography captures a transient benefit of exercise intervention on forebrain stiffness in a rat model of fetal alcohol spectrum disorders.

Katrina A MilbockerL Tyler WilliamsDiego A Caban-RiveraIan F SmithSamuel KurtzMatthew D J McGarryBertrand WattrisseElijah E W Van HoutenCurtis L Johnson Anna Y Klintsova

Published in: Alcohol, clinical & experimental research (2024)

This is the first application of MRE to measure the brain's mechanical properties in a rodent model of FASD. MRE successfully captured alcohol-related changes in forebrain stiffness and damping ratio. Additionally, MRE identified an exercise-related increase to forebrain stiffness in AE rats.

Keyphrases

magnetic resonance
high intensity
randomized controlled trial
physical activity
cerebral ischemia
resistance training
alcohol consumption
resting state
magnetic resonance imaging
functional connectivity