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Feasibility and outcomes of low-dose and low-frequency prophylaxis with recombinant extended half-life products (Fc-rFVIII and Fc-rFIX) in Ivorian children with hemophilia: Two-year experience in the setting of World Federation of Haemophilia humanitarian aid programme.

Catherine Marie LambertN'Dogomo MeitéIbrahima SanogoSébastien LobetCedric Hermans
Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2020)
This study confirms the feasibility and efficacy of low-dose and low-frequency prophylaxis in young Ivorian children with haemophilia treated with EHL CFCs donated through the WFH humanitarian aid programme. This work also highlights the crucial role of adherence and the need for appropriate education to achieve prophylaxis. Finally, it reminds the paramount objective of achieving self-sufficient, sustainable and available haemophilia replacement therapy for all worldwide.
Keyphrases
  • low dose
  • young adults
  • high dose
  • study protocol
  • healthcare
  • clinical trial
  • randomized controlled trial
  • skeletal muscle
  • glycemic control
  • cell free