Deeply-Learned Generalized Linear Models with Missing Data.
David K LimNaim U RashidJunier B OlivaJoseph G IbrahimPublished in: Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America (2023)
Deep Learning (DL) methods have dramatically increased in popularity in recent years, with significant growth in their application to various supervised learning problems. However, the greater prevalence and complexity of missing data in such datasets present significant challenges for DL methods. Here, we provide a formal treatment of missing data in the context of deeply learned generalized linear models, a supervised DL architecture for regression and classification problems. We propose a new architecture, dlglm , that is one of the first to be able to flexibly account for both ignorable and non-ignorable patterns of missingness in input features and response at training time. We demonstrate through statistical simulation that our method outperforms existing approaches for supervised learning tasks in the presence of missing not at random (MNAR) missingness. We conclude with a case study of the Bank Marketing dataset from the UCI Machine Learning Repository, in which we predict whether clients subscribed to a product based on phone survey data. Supplementary materials for this article are available online.
Keyphrases
- machine learning
- big data
- deep learning
- electronic health record
- artificial intelligence
- mental health
- healthcare
- risk factors
- working memory
- cross sectional
- social media
- virtual reality
- data analysis
- rna seq
- health information
- human immunodeficiency virus
- combination therapy
- single cell
- replacement therapy
- antiretroviral therapy