Effects of carvacrol on ketamine-induced cardiac injury in rats: an experimental study.

Tülay Ceren Ölmeztürk Karakurtİzzet EmirZehra BedirKezban Tuna Ozkaloglu ErdemHalis SuleymanCengiz SarıgülAli Sefa Mendil

Published in: Drug and chemical toxicology (2022)

Prolonged exposure to ketamine resulted in induced oxidative stress in rat heart tissue; concomitant carvacrol application could counteract the negative effects of ketamine by protecting tissues from lipid peroxidation and decreasing the inflammatory response.

Keyphrases

inflammatory response
pain management
gene expression
oxidative stress
heart failure
diabetic rats
hydrogen peroxide
left ventricular
lipopolysaccharide induced
atrial fibrillation
toll like receptor
fatty acid
chronic pain
drug induced
stress induced