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Anticancer drugs repurposed for Alzheimer's disease: a systematic review.

Antonio AncidoniIlaria BacigalupoGiulia RemoliEleonora LacortePaola PiscopoGiulia SartiMassimo CorboNicola VanacoreMarco Canevelli
Published in: Alzheimer's research & therapy (2021)
Anticancer agents are triggering growing interest in the context of repurposed therapies in AD. Several clinical trials are underway, and data are expected to be available in the near future. To date, data emerging from published clinical studies are controversial. The promising results emerging from preclinical studies and identified research protocols should be confirmed and extended by larger, adequately designed, and high-quality clinical trials.
Keyphrases
  • clinical trial
  • electronic health record
  • big data
  • phase ii
  • open label
  • cognitive decline
  • randomized controlled trial
  • machine learning
  • double blind
  • mesenchymal stem cells