Phenotyping Type 2 Diabetes in Terms of Myocardial Insulin Resistance and Its Potential Cardiovascular Consequences: A New Strategy Based on 18 F-FDG PET/CT.
José Raúl HeranceRafael SimòMayra Alejandra VelasquezBruno PaunDaniel García-LeonCarolina AparicioRoso MarésOlga Simó-ServatJoan Castell-ConesaCristina HernandezSantiago Aguade-BruixPublished in: Journal of personalized medicine (2022)
F-FDG PET combined with HEC is a reliable method for identifying patients with mIR. This subgroup of patients was found to be specifically at high risk of developing cardiovascular events and showed myocardial structural changes. Moreover, the gold-standard HOMA-IR index was only associated with mIR in this subgroup of patients. Our results open up a new avenue for stratifying patients with cardiovascular risk in T2D.
Keyphrases
- type diabetes
- cardiovascular events
- end stage renal disease
- insulin resistance
- ejection fraction
- newly diagnosed
- cell proliferation
- cardiovascular disease
- coronary artery disease
- long non coding rna
- peritoneal dialysis
- left ventricular
- adipose tissue
- randomized controlled trial
- computed tomography
- clinical trial
- pet ct
- long noncoding rna
- minimally invasive
- patient reported