Imaging endpoints for clinical trials in MacTel type 2.

Daniel PauleikhoffLaurenz PauleikhoffEmily Y Chew

Published in: Eye (London, England) (2021)

The analysis of the area of photoreceptor loss on en face OCT is the most reliable imaging endpoint for treatment trials in MacTel. This method is already being used in ongoing randomized trials.

Keyphrases

clinical trial
high resolution
randomized controlled trial
mass spectrometry
diabetic retinopathy
fluorescence imaging
phase iii
double blind