Altered Expression of Intestinal Tight Junctions in Patients with Chronic Kidney Disease: A Pathogenetic Mechanism of Intestinal Hyperpermeability.

Georgia-Andriana Georgopoulou Marios PapasotiriouPinelopi BosganaAnne-Lise Delastic Eleni-Evangelia KoufouEvangelos PapachristouDimitrios S GoumenosPeriklis DavlourosHelen P KoureaVasiliki ZolotaKonstantinos ThomopoulosAthanasia Mouzaki Stelios F Assimakopoulos

Published in: Biomedicines (2024)

The expression of occludin and claudin-1 in enterocytes is significantly reduced in patients with CKD, contributing to systemic endotoxemia and inflammatory responses in these patients.

Keyphrases

poor prognosis
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
prognostic factors
binding protein
peritoneal dialysis
single molecule
inflammatory response