Plasma level of lipocalin 2 is increased in neovascular age-related macular degeneration patients, particularly those with macular fibrosis.
Mei ChenNan YangJudith LechnerLevente TothRuth HoggGiuliana SilvestriUsha ChakravarthyHeping XuPublished in: Immunity & ageing : I & A (2020)
Our results suggest that higher plasma levels of LCN2 in nAMD are related to ageing and increased population of circulating neutrophils. Our results also suggest that higher levels of LCN2 may increase the risk of macular fibrosis in nAMD.