Biologic-Induced Infections in Inflammatory Bowel Disease: The TNF-α Antagonists.
Sean M McConachieSheila M WilhelmAshish BhargavaPramodini B Kale-PradhanPublished in: The Annals of pharmacotherapy (2018)
TNF-α antagonists are associated with an increased risk of opportunistic infection, although this risk has not been demonstrated conclusively in randomized controlled trials. Knowledge of concomitant risk factors, mechanism of infectious risk, and available treatment options can improve patient care in the clinical setting.