Mechanisms underlying induction of allergic sensitization by Pru p 3.
L TordesillasN Cubells-BaezaC Gómez-CasadoC BerinV EstebanW BarcikL O'MahonyC RamirezL F PaciosM Garrido-ArandiaArazeli Diaz PeralesPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017)
The Pru p 3 lipid-ligand could act as an adjuvant to promote sensitization to Pru p 3, through its recognition by CD1d receptors. This intrinsic adjuvant activity of the accompanying lipid cargo could be a general essential feature of the mechanism underlying the phenomenon of allergenicity.