Four-Factor Prothrombin Complex Concentrate Reduces Time to Procedure in Vitamin K Antagonist-Treated Patients Experiencing Gastrointestinal Bleeding: A Post Hoc Analysis of Two Randomized Controlled Trials.

Majed A RefaaiTruptesh H KothariShana StraubJacob FalconRavi SarodeJoshua N GoldsteinAndres BrainskyLaurel OmertMartin L LeeTruman J Milling

Published in: Emergency medicine international (2017)

In this analysis of patients with acute/severe gastrointestinal bleeding requiring urgent VKA reversal prior to an invasive procedure, 4F-PCC (compared with plasma) was associated with smaller infusion volumes, shorter infusion times, and reduced time to procedure.

Keyphrases

end stage renal disease
minimally invasive
newly diagnosed
randomized controlled trial
low dose
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
systematic review
early onset
patient reported outcomes
study protocol
meta analyses