Efficacy and safety of denosumab versus zoledronic acid in OI adults: A prospective, open-label, randomized study.
Xiaoyun LinJing HuBingna ZhouXiaojie WangQian ZhangYan JiangOu WangWeibo XiaXiaoping XingMei LiPublished in: The Journal of clinical endocrinology and metabolism (2024)
Denosumab effectively increases aBMD in OI adults, with similar efficacy to zoledronic acid. Long-term and large-sample studies are needed to confirm the anti-fracture efficacy and safety of denosumab in adult OI patients.