Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy.
Natalia PakharukovaBrittany N ThomasHarsh BansiaLinus LiRinat R AbzalimovJihee KimAlem W KahsaiBiswaranjan PaniDana K BassfordShibo LiuXingdong ZhangAmédée Des GeorgesRobert J LefkowitzPublished in: bioRxiv : the preprint server for biology (2024)
Beta-arrestin 1 uses two distinct sites to bind the SH3 domain of Src and drive relief of Src autoinhibition.
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