Discovery of Biomarkers and Potential Mechanisms of Agarwood Incense Smoke Intervention by Untargeted Metabolomics and Network Pharmacology.

Meiyue DongHaitao DuXueling LiLing ZhangXiaoming WangZhenguo WangHaiqiang Jiang

Published in: Drug design, development and therapy (2022)

In conclusion, this study enhanced current understanding of the change of metabolic markers after AIS intervention. Meanwhile, it also confirmed the feasibility of combining metabolomics and network pharmacology to identify active components and elucidate the material basis of biomarkers and mechanisms.

Keyphrases

mass spectrometry
randomized controlled trial
small molecule
liquid chromatography
high throughput
high resolution
gas chromatography mass spectrometry
human health
risk assessment
high resolution mass spectrometry
tandem mass spectrometry