PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPARγ SUMOylation.
Bo XieXinyu LiuJie YangJinke ChengJianmin GuSong XuePublished in: BMC cell biology (2018)
Collectively, our findings demonstrate the crucial role of PIAS1-mediated PPARγ SUMOylation in protecting against myocardial IRI.